iPTMnet Report for Q8N2Y8 (RUSC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N2Y8 / RUSC2_HUMAN
Protein Name AP-4 complex accessory subunit RUSC2
Gene Name Name: RUSC2
Synonyms:KIAA0375;
Organism Homo sapiens (Human)

PRO ID PR:Q8N2Y8
DAG View
PRO Name AP-4 complex accessory subunit RUSC2 (human)
Definition An AP-4 complex accessory subunit RUSC2 that is encoded in the genome of human.
Short Label hRUSC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N2Y8 (RUSC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
T162 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
T474 Phosphorylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
S536 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...18220336
S543 Phosphorylation PhosphoSitePlus   UniProt 23186163
S557 Phosphorylation PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus   UniProt 23186163
S574 Phosphorylation PhosphoSitePlus
S656 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S660 Phosphorylation PhosphoSitePlus
Y720 Phosphorylation PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
S753 Phosphorylation PhosphoSitePlus
T754 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
Y780 Phosphorylation PhosphoSitePlus
S781 Phosphorylation PhosphoSitePlus   UniProt 23186163
K839 Ubiquitination PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
S890 Phosphorylation PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
T1013 Phosphorylation PhosphoSitePlus
S1014 Phosphorylation PhosphoSitePlus
S1026 Phosphorylation PhosphoSitePlus
Y1089 Phosphorylation PhosphoSitePlus
K1230 Ubiquitination PhosphoSitePlus
T1247 Phosphorylation PhosphoSitePlus
S1347 Phosphorylation PhosphoSitePlus
S1368 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1380 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
K1385 Ubiquitination PhosphoSitePlus
S1441 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T161 A161 Biomuta DOID:363 / uterine cancer [ tcga ]
T482 M482 Biomuta DOID:363 / uterine cancer [ tcga ]
S506 R506 Biomuta DOID:363 / uterine cancer [ tcga ]
S559 L559 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S574 L574 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S660 I660 Biomuta DOID:3571 / liver cancer [ icgc ]
S1368 L1368 Biomuta DOID:5041 / esophageal cancer [ icgc ]