iPTMnet Report for Q8N2S1 (LTBP4)
Protein Information
| UniProt AC / UniProt ID | Q8N2S1 / LTBP4_HUMAN |
| Protein Name | Latent-transforming growth factor beta-binding protein 4 precursor |
| Gene Name | Name: LTBP4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N2S1 |
| PRO Name | latent-transforming growth factor beta-binding protein 4 (human) |
| Definition | A latent-transforming growth factor beta-binding protein 4 that is encoded in the genome of human. |
| Short Label | hLTBP4 |
| Category | organism-gene |
DAG ViewQ8N2S1 (LTBP4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S31 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S33 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S35 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S45 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S221 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S231 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| T268 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| S273 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| Y280 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S281 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T346 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| S468 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T476 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| S487 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T497 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| S501 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T507 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S530 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T535 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S542 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S579 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T833 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1170 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1266 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1442 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1449 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1452 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1483 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1486 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S1486 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1496 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T57 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K5 | Methylation | score1 | PhosphoSitePlus | |||
| S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S30 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S35 | R35 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S221 | N221 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S284 | L284 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T507 | I507 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K1266 | N1266 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T1496 | P1496 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
