iPTMnet Report for Q8N2K0 (ABHD12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N2K0 / ABD12_HUMAN
Protein Name Lysophosphatidylserine lipase ABHD12
Gene Name Name: ABHD12
Synonyms:C20orf22;
Organism Homo sapiens (Human)

PRO ID PR:Q8N2K0
DAG View
PRO Name lysophosphatidylserine lipase ABHD12 (human)
Definition A lysophosphatidylserine lipase ABHD12 that is encoded in the genome of human.
Short Label hABHD12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N2K0 (ABHD12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation PhosphoSitePlus
S25 O-Glycosylation GlyGen 34019948, 29351928
T43 Phosphorylation PhosphoSitePlus
Y83 Phosphorylation IEDB 32387766
Y110 Phosphorylation PhosphoSitePlus
N123 N-Glycosylation GlyGen 29741879
S195 Phosphorylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y83 F83 Biomuta DOID:1324 / lung cancer [ cosmic ]
S246 F246 Biomuta DOID:4159 / skin cancer [ cosmic ]
K319 N319 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]