iPTMnet Report for Q8N2H9 (PELI3)
Protein Information
UniProt AC / UniProt ID | Q8N2H9 / PELI3_HUMAN |
Protein Name | E3 ubiquitin-protein ligase pellino homolog 3 |
Gene Name | Name: PELI3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N2H9 |
PRO Name | E3 ubiquitin-protein ligase pellino homolog 3 (human) |
Definition | An E3 ubiquitin-protein ligase pellino homolog 3 that is encoded in the genome of human. |
Short Label | hPELI3 |
Category | organism-gene |
Q8N2H9 (PELI3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Phosphorylation | score1 | PRO | ||||
S11 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y130 | Phosphorylation | score1 | PhosphoSitePlus | |||
S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
T168 | Phosphorylation | score1 | PhosphoSitePlus | |||
S169 | Phosphorylation | score1 | PhosphoSitePlus | |||
S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
K316 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S11 | C11 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S129 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T168 | M168 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |