iPTMnet Report for Q8N2H9 (PELI3)
Protein Information
| UniProt AC / UniProt ID | Q8N2H9 / PELI3_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase pellino homolog 3 |
| Gene Name | Name: PELI3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N2H9 |
| PRO Name | E3 ubiquitin-protein ligase pellino homolog 3 (human) |
| Definition | An E3 ubiquitin-protein ligase pellino homolog 3 that is encoded in the genome of human. |
| Short Label | hPELI3 |
| Category | organism-gene |
Q8N2H9 (PELI3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Phosphorylation | score1 | PRO | ||||
| S11 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T168 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S169 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K316 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S11 | C11 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S129 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T168 | M168 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View