iPTMnet Report for Q8N264 (ARHGAP24)
Protein Information
| UniProt AC / UniProt ID | Q8N264 / RHG24_HUMAN |
| Protein Name | Rho GTPase-activating protein 24 |
| Gene Name | Name: ARHGAP24 Synonyms:FILGAP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N264 |
| PRO Name | Rho GTPase-activating protein 24 (human) |
| Definition | A Rho GTPase-activating protein 24 that is encoded in the genome of human. |
| Short Label | hARHGAP24 |
| Category | organism-gene |
DAG ViewQ8N264 (ARHGAP24) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T62 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T354 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S371 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S391 | Phosphorylation | Q13464 (ROCK1) | score3 | neXtProt PhosphoSitePlus Signor UniProt | 16862148 | |
| T393 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S398 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S402 | Phosphorylation | Q13464 (ROCK1) | score4 | neXtProt PhosphoSitePlus RLIMS-P Signor UniProt | 26359494, 16862148 | |
| S406 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S413 | Phosphorylation | Q13464 (ROCK1) | score3 | neXtProt PhosphoSitePlus Signor UniProt | 16862148 | |
| S415 | O-Glycosylation | score1 | GlyGen | 35254053 | ||
| S415 | Phosphorylation | Q13464 (ROCK1) | score4 | neXtProt PhosphoSitePlus Signor UniProt | 16862148, 23186163 | |
| K421 | Acetylation | score1 | PhosphoSitePlus | |||
| K422 | Acetylation | score1 | PhosphoSitePlus | |||
| S437 | Phosphorylation | Q13464 (ROCK1) | score3 | neXtProt PhosphoSitePlus Signor UniProt | 16862148 | |
| T452 | Phosphorylation | Q13464 (ROCK1) | score3 | neXtProt PhosphoSitePlus Signor UniProt | 16862148 | |
| S464 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y508 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S573 | Phosphorylation | Q13464 (ROCK1) | score1 | Signor | 16862148 | |
| S574 | Phosphorylation | Q13464 (ROCK1) | score1 | Signor | 16862148 | |
| T575 | Phosphorylation | Q13464 (ROCK1) | score1 | Signor | 16862148 | |
| T576 | Phosphorylation | Q13464 (ROCK1) | score1 | Signor | 16862148 | |
| T577 | Phosphorylation | Q13464 (ROCK1) | score1 | Signor | 16862148 | |
| T624 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S627 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S727 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T728 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S391 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| S402 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| S413 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| S415 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| S437 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| T452 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| S573 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| S574 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| T575 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| T576 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 | |
| T577 | Phosphorylation | Q13464 (ROCK1) | score1 | HPRD | 16862148 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S369 | N369 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S371 | G371 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S371 | I371 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S391 | F391 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K422 | N422 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K422 | Q422 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T577 | P577 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S727 | Y727 | Biomuta | [ cosmic ] | |
| T728 | M728 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] |
