Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N228 / SCML4_HUMAN
Protein Name Sex comb on midleg-like protein 4
Gene Name Name: SCML4
Organism Homo sapiens (Human)

PRO ID PR:Q8N228
DAG View
PRO Name sex comb on midleg-like protein 4 (human)
Definition A sex comb on midleg-like protein 4 that is encoded in the genome of human.
Short Label hSCML4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N228 (SCML4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S65 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
Y236 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
T286 Phosphorylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S162 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S164 L164 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S164 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S274 F274 Biomuta DOID:4159 / skin cancer [ cosmic ]