iPTMnet Report for Q8N1N4 (KRT78)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N1N4 / K2C78_HUMAN
Protein Name Keratin, type II cytoskeletal 78
Gene Name Name: KRT78
Synonyms:K5B,KB40;
Organism Homo sapiens (Human)

PRO ID PR:Q8N1N4
DAG View
PRO Name keratin, type II cytoskeletal 78 (human)
Definition A keratin, type II cytoskeletal 78 that is encoded in the genome of human.
Short Label hKRT78
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N1N4 (KRT78) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
R52 Methylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
K128 Acetylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
T306 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
Y413 Phosphorylation PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
T516 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T259 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 I26 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R52 G52 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R52 C52 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R52 H52 Biomuta DOID:1319 / brain cancer [ icgc ]
S124 F124 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y304 H304 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T306 I306 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]