iPTMnet Report for Q8N1I0 (DOCK4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N1I0 / DOCK4_HUMAN
Protein Name Dedicator of cytokinesis protein 4
Gene Name Name: DOCK4
Synonyms:KIAA0716;
Organism Homo sapiens (Human)

PRO ID PR:Q8N1I0
DAG View
PRO Name dedicator of cytokinesis protein 4 (human)
Definition A dedicator of cytokinesis protein 4 that is encoded in the genome of human.
Short Label hDOCK4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N1I0 (DOCK4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K101 Ubiquitination PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
Y375 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
T570 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
T576 Phosphorylation PhosphoSitePlus
K596 Ubiquitination PhosphoSitePlus
Y675 Phosphorylation PhosphoSitePlus
Y821 Phosphorylation PhosphoSitePlus
T889 Phosphorylation PhosphoSitePlus
T894 Phosphorylation PhosphoSitePlus
K1109 Ubiquitination PhosphoSitePlus
K1113 Ubiquitination PhosphoSitePlus
Y1165 Phosphorylation PhosphoSitePlus
S1301 Phosphorylation PhosphoSitePlus
K1574 Ubiquitination PhosphoSitePlus
S1599 Phosphorylation PhosphoSitePlus
S1607 Phosphorylation PhosphoSitePlus
S1614 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S1618 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S1620 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S1631 Phosphorylation PhosphoSitePlus
S1700 Phosphorylation PhosphoSitePlus
S1704 Phosphorylation PhosphoSitePlus
S1717 Phosphorylation PhosphoSitePlus
S1724 Phosphorylation PhosphoSitePlus
Y1727 Phosphorylation PhosphoSitePlus
S1750 Phosphorylation PhosphoSitePlus
S1769 Phosphorylation PhosphoSitePlus
S1787 O-Glycosylation GlyGen 28657654, 35254053
S1787 Phosphorylation PhosphoSitePlus
T1797 O-Glycosylation GlyGen 32938750, 28657654, 35254053
T1804 Phosphorylation PhosphoSitePlus
S1806 Phosphorylation PhosphoSitePlus
S1808 Phosphorylation PhosphoSitePlus
S1810 Phosphorylation PhosphoSitePlus
S1815 Phosphorylation PhosphoSitePlus
Y1831 Phosphorylation PhosphoSitePlus
S1833 Phosphorylation PhosphoSitePlus
T1899 Phosphorylation PhosphoSitePlus
Y1903 Phosphorylation PhosphoSitePlus
Y1906 Phosphorylation PhosphoSitePlus
S1921 O-Glycosylation GlyGen 28657654, 35254053
S1921 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1614 Phosphorylation HPRD 18669648
S1618 Phosphorylation HPRD 18669648
S1620 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S360 F360 Biomuta DOID:4159 / skin cancer [ cosmic ]
S506 Y506 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S506 F506 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1631 G1631 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1704 C1704 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1724 I1724 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1804 M1804 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S1810 L1810 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1833 L1833 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y1906 C1906 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
Y1906 F1906 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]