iPTMnet Report for Q8N183 (NDUFAF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N183 / NDUF2_HUMAN
Protein Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 precursor
Gene Name Name: NDUFAF2
Synonyms:NDUFA12L;
Organism Homo sapiens (Human)

PRO ID PR:Q8N183
DAG View
PRO Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (human)
Definition An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 that is encoded in the genome of human.
Short Label hNDUFAF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N183 (NDUFAF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 O-Glycosylation GlyGen 28510447, 33465208
K31 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
T127 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y137 Phosphorylation PhosphoSitePlus
S144 O-Glycosylation GlyGen 28510447, 33465208
S144 Phosphorylation PhosphoSitePlus
S148 O-Glycosylation GlyGen 31373491, 33465208
S149 O-Glycosylation GlyGen 31373491, 33465208
T150 O-Glycosylation GlyGen 31373491, 33465208


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K39 N39 Biomuta DOID:363 / uterine cancer [ icgc ]
T45 S45 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T69 I69 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K101 N101 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y137 C137 Biomuta DOID:9256 / colorectal cancer [ cosmic ]