Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N163 / CCAR2_HUMAN
Protein Name Cell cycle and apoptosis regulator protein 2
Gene Name Name: CCAR2
Synonyms:DBC1,KIAA1967;
Organism Homo sapiens (Human)

PRO ID PR:Q8N163
DAG View
PRO Name cell cycle and apoptosis regulator protein 2 (human)
Definition A cell cycle and apoptosis regulator protein 2 that is encoded in the genome of human.
Short Label hCCAR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N163 (CCAR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R16 Methylation PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus   UniProt 19690332, 20068231
K54 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K112 Acetylation PhosphoSitePlus   UniProt 24126058
K112 Ubiquitination PhosphoSitePlus
T115 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
K123 Methylation PhosphoSitePlus   UniProt 24129315
K123 Ubiquitination PhosphoSitePlus
S124 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 18669648, 23186163, ...20068231
K138 Acetylation PhosphoSitePlus
K138 Methylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
R180 Methylation PhosphoSitePlus   UniProt 24129315
R184 Methylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
R206 Methylation PhosphoSitePlus
K215 Acetylation PhosphoSitePlus   UniProt 24126058, 19608861
K215 Methylation PhosphoSitePlus
R218 Methylation PhosphoSitePlus
K287 Acetylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
Y322 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
Y410 Phosphorylation PhosphoSitePlus
T454 Phosphorylation Q13535 (ATR) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   UniProt 22465953, 23186163, 27503537, ...15302935, 18077418, 24129246, 25361978, 22735644, 30245854, 26194823, 24962073
S478 Phosphorylation phospho.ELM 18669648
T484 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
T488 Phosphorylation PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K585 Acetylation PhosphoSitePlus
K591 Sumoylation PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
K616 Ubiquitination PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
S627 Phosphorylation PhosphoSitePlus   UniProt 24275569
S640 Phosphorylation PhosphoSitePlus
K667 Ubiquitination PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
S675 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 15302935, ...18669648, 19690332, 20068231
S678 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18669648, 19690332, 20068231
S681 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...19690332, 20068231
S686 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K742 Ubiquitination PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
T797 Phosphorylation PhosphoSitePlus
K800 Ubiquitination PhosphoSitePlus
S804 Phosphorylation PhosphoSitePlus
S808 Phosphorylation PhosphoSitePlus   UniProt 23186163
S814 Phosphorylation PhosphoSitePlus
Y828 Phosphorylation PhosphoSitePlus
K832 Ubiquitination PhosphoSitePlus
K839 Ubiquitination PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
R865 Methylation PhosphoSitePlus
T897 Phosphorylation PhosphoSitePlus   UniProt 23186163
K909 Acetylation PhosphoSitePlus
K909 Ubiquitination PhosphoSitePlus
K916 Ubiquitination PhosphoSitePlus
S922 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T35 Phosphorylation HPRD 20068231
S124 Phosphorylation HPRD 19651622, 18669648, 17287340, ...20068231
S478 Phosphorylation HPRD 18669648
T484 Phosphorylation HPRD 20068231
T488 Phosphorylation HPRD 17081983
T493 Phosphorylation HPRD 17081983
T495 Phosphorylation HPRD 20058876, 17081983
S671 Phosphorylation HPRD 17081983, 20068231
S675 Phosphorylation HPRD 19413330, 15302935, 18452278, ...19651622, 18669648, 20166139, 20068231
S678 Phosphorylation HPRD 19413330, 17322306, 18767875, ...20058876, 19664995, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231
S681 Phosphorylation HPRD 19413330, 17322306, 18767875, ...18452278, 19651622, 18669648, 20068231
S686 Phosphorylation HPRD 20068231
S808 Phosphorylation HPRD 20068231
T897 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046581 (hCCAR2/Phos:1) pT454 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q8N163 (CCAR2) T454 Q96EB6 (SIRT1) unknown eFIP 30245854
Phosphorylation Q8N163 (CCAR2) T454 Q96EB6 (SIRT1) unknown eFIP 25361978