iPTMnet Report for Q8N142 (ADSS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N142 / PURA1_HUMAN
Protein Name Adenylosuccinate synthetase isozyme 1
Gene Name Name: ADSS1
Synonyms:ADSSL1;
Organism Homo sapiens (Human)

PRO ID PR:Q8N142
DAG View
PRO Name adenylosuccinate synthetase isozyme 1 (human)
Definition An adenylosuccinate synthetase isozyme 1 that is encoded in the genome of human.
Short Label hADSS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N142 (ADSS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K18 Acetylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
K174 Acetylation PhosphoSitePlus
K248 Acetylation PhosphoSitePlus
Y388 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y403 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y388 Phosphorylation HPRD 18083107
Site PTM Type PTM Enzyme Score Source PMID
T57 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
T68 Phosphorylation PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
Y431 Phosphorylation HPRD 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S449 L449 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S449 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]