iPTMnet Report for Q8N103 (TAGAP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N103 / TAGAP_HUMAN
Protein Name T-cell activation Rho GTPase-activating protein
Gene Name Name: TAGAP
Synonyms:TAGAP1;ORFNames:FKSG15;
Organism Homo sapiens (Human)

PRO ID PR:Q8N103
DAG View
PRO Name T-cell activation Rho GTPase-activating protein (human)
Definition A T-cell activation Rho GTPase-activating protein that is encoded in the genome of human.
Short Label hTAGAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N103 (TAGAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
K129 Acetylation PhosphoSitePlus
Y310 Phosphorylation PhosphoSitePlus
S354 Phosphorylation IEDB   PhosphoSitePlus 27920218
S377 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus   UniProt 24275569
S415 Phosphorylation PhosphoSitePlus
K458 Acetylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
K494 Acetylation PhosphoSitePlus
K499 Acetylation PhosphoSitePlus
S501 O-Glycosylation GlyGen 30379171
S510 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
S700 O-Glycosylation GlyGen 30379171
S714 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S479 G479 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S490 Y490 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K499 N499 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S501 G501 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S510 Y510 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S700 F700 Biomuta DOID:4159 / skin cancer [ cosmic ]