iPTMnet Report for Q8N0X2 (SPAG16)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N0X2 / SPG16_HUMAN
Protein Name Sperm-associated antigen 16 protein
Gene Name Name: SPAG16
Synonyms:PF20;
Organism Homo sapiens (Human)

PRO ID PR:Q8N0X2
DAG View
PRO Name sperm-associated antigen 16 protein (human)
Definition A sperm-associated antigen 16 protein that is encoded in the genome of human.
Short Label hSPAG16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N0X2 (SPAG16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K96 Ubiquitination PhosphoSitePlus
C114 Methylation IEDB 31844290
K139 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
Y271 Phosphorylation PhosphoSitePlus
T292 O-Glycosylation GlyGen 30379171
T313 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
K332 Acetylation PhosphoSitePlus
S436 O-Glycosylation GlyGen 30379171
T501 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
Y517 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C114 R114 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T244 N244 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S245 F245 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S270 I270 Biomuta DOID:4159 / skin cancer [ cosmic ]
T292 I292 Biomuta DOID:4159 / skin cancer [ cosmic ]
S331 F331 Biomuta DOID:4159 / skin cancer [ cosmic ]
S436 N436 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S503 F503 Biomuta DOID:4159 / skin cancer [ cosmic ]