iPTMnet Report for Q8N0V4 (LGI2)
Protein Information
| UniProt AC / UniProt ID | Q8N0V4 / LGI2_HUMAN |
| Protein Name | Leucine-rich repeat LGI family member 2 precursor |
| Gene Name | Name: LGI2 Synonyms:KIAA1916,LGIL2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N0V4 |
| PRO Name | leucine-rich repeat LGI family member 2 (human) |
| Definition | A leucine-rich repeat LGI family member 2 that is encoded in the genome of human. |
| Short Label | hLGI2 |
| Category | organism-gene |
DAG ViewQ8N0V4 (LGI2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K174 | Acetylation | score1 | PhosphoSitePlus | |||
| K176 | Acetylation | score1 | PhosphoSitePlus | |||
| T185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y269 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T273 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T431 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T273 | I273 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T431 | I431 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] |
