Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8N0S6 / CENPL_HUMAN
Protein Name Centromere protein L
Gene Name Name: CENPL
Organism Homo sapiens (Human)

DAG View
PRO Name centromere protein L (human)
Definition A centromere protein L that is encoded in the genome of human.
Short Label hCENPL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8N0S6 (CENPL) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus   UniProt 23186163
T43 Phosphorylation PhosphoSitePlus   UniProt 23186163
K48 Ubiquitination PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus   UniProt 20068231
K63 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S38 Phosphorylation HPRD 20068231
S39 Phosphorylation HPRD 20068231
T43 Phosphorylation HPRD 20068231
S53 Phosphorylation HPRD 20068231
T73 Phosphorylation HPRD 20068231
Y75 Phosphorylation HPRD 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 F3 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S53 L53 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S53 * Biomuta DOID:3571 / liver cancer [ icgc ]