Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZX4 / TAF1L_HUMAN
Protein Name Transcription initiation factor TFIID subunit 1-like
Gene Name Name: TAF1L
Organism Homo sapiens (Human)

PRO ID PR:Q8IZX4
DAG View
PRO Name transcription initiation factor TFIID subunit 1-like (human)
Definition A transcription initiation factor TFIID 210 kDa subunit that is encoded in the genome of human.
Short Label hTAF1L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZX4 (TAF1L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K257 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
T390 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
T564 Phosphorylation PhosphoSitePlus
K720 Ubiquitination PhosphoSitePlus
K724 Acetylation PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K851 Ubiquitination PhosphoSitePlus
T874 Phosphorylation PhosphoSitePlus
K1005 Ubiquitination PhosphoSitePlus
K1028 Ubiquitination PhosphoSitePlus
S1073 Phosphorylation PhosphoSitePlus
K1130 Ubiquitination PhosphoSitePlus
S1137 Phosphorylation PhosphoSitePlus
T1173 Phosphorylation PhosphoSitePlus
S1174 Phosphorylation PhosphoSitePlus
K1263 Acetylation PhosphoSitePlus
S1359 Phosphorylation PhosphoSitePlus
K1366 Acetylation PhosphoSitePlus
K1373 Acetylation PhosphoSitePlus
Y1385 Phosphorylation PhosphoSitePlus
T1398 Phosphorylation PhosphoSitePlus
T1403 Phosphorylation PhosphoSitePlus
S1410 Phosphorylation PhosphoSitePlus
Y1560 Phosphorylation PhosphoSitePlus
Y1581 Phosphorylation PhosphoSitePlus
S1583 Phosphorylation PhosphoSitePlus
S1652 Phosphorylation PhosphoSitePlus
Y1669 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K269 E269 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S306 R306 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K720 N720 Biomuta DOID:363 / uterine cancer [ tcga ]
K1028 E1028 Biomuta DOID:4159 / skin cancer [ icgc ]
S1073 Y1073 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K1373 N1373 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T1398 A1398 Biomuta DOID:1324 / lung cancer [ icgc, tcga ]
T1403 M1403 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:10534 / stomach cancer [ tcga ] DOID:5041 / esophageal cancer [ icgc ]
S1652 I1652 Biomuta DOID:1612 / breast cancer [ tcga ]