iPTMnet Report for Q8IZS8 (CACNA2D3)
Protein Information
| UniProt AC / UniProt ID | Q8IZS8 / CA2D3_HUMAN |
| Protein Name | Voltage-dependent calcium channel subunit alpha-2/delta-3 precursor |
| Gene Name | Name: CACNA2D3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IZS8 |
| PRO Name | voltage-dependent calcium channel subunit alpha-2/delta-3 (human) |
| Definition | A voltage-dependent calcium channel subunit alpha-2/delta-3 that is encoded in the genome of human. |
| Short Label | hCACNA2D3 |
| Category | organism-gene |
DAG ViewQ8IZS8 (CACNA2D3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K101 | Acetylation | score1 | PhosphoSitePlus | |||
| K119 | Acetylation | score1 | PhosphoSitePlus | |||
| K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y247 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T468 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y543 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T730 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S812 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K141 | T141 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S812 | F812 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S812 | Y812 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
