iPTMnet Report for Q8IZQ1 (WDFY3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZQ1 / WDFY3_HUMAN
Protein Name WD repeat and FYVE domain-containing protein 3
Gene Name Name: WDFY3
Synonyms:KIAA0993;
Organism Homo sapiens (Human)

PRO ID PR:Q8IZQ1
DAG View
PRO Name WD repeat and FYVE domain-containing protein 3 (human)
Definition A WD repeat and FYVE domain-containing protein 3 that is encoded in the genome of human.
Short Label hWDFY3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZQ1 (WDFY3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
T81 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
T524 Phosphorylation PhosphoSitePlus
Y653 Phosphorylation PhosphoSitePlus
Y813 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S815 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S817 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T818 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y822 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K825 Ubiquitination PhosphoSitePlus
S932 Phosphorylation PhosphoSitePlus
Y963 Phosphorylation PhosphoSitePlus
S970 Phosphorylation PhosphoSitePlus
S984 Phosphorylation PhosphoSitePlus
K1006 Ubiquitination PhosphoSitePlus
S1011 Phosphorylation phospho.ELM 17081983
T1020 Phosphorylation PhosphoSitePlus
K1353 Ubiquitination PhosphoSitePlus
T1364 Phosphorylation PhosphoSitePlus
K1643 Ubiquitination PhosphoSitePlus
S1648 Phosphorylation PhosphoSitePlus
S1696 Phosphorylation PhosphoSitePlus
S1699 Phosphorylation PhosphoSitePlus
S1709 Phosphorylation PhosphoSitePlus
S1940 Phosphorylation PhosphoSitePlus
S1942 Phosphorylation PhosphoSitePlus
Y1944 Phosphorylation PhosphoSitePlus
K1950 Ubiquitination PhosphoSitePlus
S2083 Phosphorylation PhosphoSitePlus
S2177 Phosphorylation PhosphoSitePlus
S2184 Phosphorylation PhosphoSitePlus
Y2185 Phosphorylation PhosphoSitePlus
S2190 Phosphorylation PhosphoSitePlus
K2272 Ubiquitination PhosphoSitePlus
S2277 Phosphorylation PhosphoSitePlus
S2278 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2283 Phosphorylation PhosphoSitePlus
S2434 Phosphorylation PhosphoSitePlus
S2490 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2492 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T2573 Phosphorylation PhosphoSitePlus
T2807 Phosphorylation PhosphoSitePlus
S2980 O-Glycosylation GlyGen 29351928
S2990 O-Glycosylation GlyGen 29351928
S3308 Phosphorylation PhosphoSitePlus
T3319 Phosphorylation PhosphoSitePlus
T3324 Phosphorylation PhosphoSitePlus
S3326 Phosphorylation PhosphoSitePlus
S3328 Phosphorylation PhosphoSitePlus
S3335 Phosphorylation PhosphoSitePlus
S3339 Phosphorylation PhosphoSitePlus   UniProt 23186163
R3472 Methylation PhosphoSitePlus
S3501 Phosphorylation PhosphoSitePlus
S3519 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y813 Phosphorylation HPRD 18669648
S815 Phosphorylation HPRD 18669648
S817 Phosphorylation HPRD 18669648
T818 Phosphorylation HPRD 18669648
Y822 Phosphorylation HPRD 18669648
S1015 Phosphorylation HPRD 17081983
T1016 Phosphorylation HPRD 17081983
T1020 Phosphorylation HPRD 17081983
S2277 Phosphorylation HPRD 18691976
S2490 Phosphorylation HPRD 18669648
S2492 Phosphorylation HPRD 18669648
S3339 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S271 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S815 F815 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T818 A818 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K825 E825 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1011 F1011 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1699 P1699 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1940 T1940 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y1944 C1944 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2177 L2177 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2184 G2184 Biomuta [ cosmic ]
T2573 S2573 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T3324 A3324 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R3472 I3472 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
R3472 T3472 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]