Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8IZL9 / CDK20_HUMAN
Protein Name Cyclin-dependent kinase 20
Gene Name Name: CDK20
Organism Homo sapiens (Human)

DAG View
PRO Name cyclin-dependent kinase 20 (human)
Definition A cyclin-dependent kinase 20 that is encoded in the genome of human.
Short Label hCDK20
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8IZL9 (CDK20) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus

Q8IZL9 (CDK20) as PTM Enzyme

Substrate Site Score Source PMID
P24941 (CDK2) T160 HPRD   PhosphoSitePlus   Signor 18767875, 18452278, 20068231, ...20466538, 14597612
Q9UPZ9 (CILK1) T157 PhosphoSitePlus   Signor 16954377, 15988018

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P10721 (KIT) Y900 Q8IZL9 (CDK20) unknown eFIP 12878163

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K53 R53 Biomuta DOID:1324 / lung cancer [ cosmic ]