iPTMnet Report Q8IZL9 CDK20

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8IZL9 / CDK20_HUMAN
Protein Name	Cyclin-dependent kinase 20
Gene Name	Name: CDK20 Synonyms:CCRK,CDCH;
Organism	Homo sapiens (Human)

PRO ID	PR:Q8IZL9 DAG View
PRO Name	cyclin-dependent kinase 20 (human)
Definition	A cyclin-dependent kinase 20 that is encoded in the genome of human.
Short Label	hCDK20
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8IZL9 (CDK20) as Substrate

Q8IZL9

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y4	Phosphorylation		score1	PhosphoSitePlus
	K33	Ubiquitination		score1	PhosphoSitePlus
	K53	Ubiquitination		score1	PhosphoSitePlus
	K129	Ubiquitination		score1	PhosphoSitePlus
	T161	Phosphorylation		score1	PhosphoSitePlus
	K239	Ubiquitination		score1	PhosphoSitePlus
	K281	Ubiquitination		score1	PhosphoSitePlus

Q8IZL9 (CDK20) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	P24941 (CDK2)	T160	score4	HPRD PhosphoSitePlus Signor	18767875, 18452278, 20068231, ...20466538, 14597612
	Q9UPZ9 (CILK1)	T157	score4	PhosphoSitePlus Signor	16954377, 15988018

PTM-dependent PPI

	PTM type	Substrate	Site	Interactant	Association type	Source	PMID
	Phosphorylation	P10721 (KIT)	Y900	Q8IZL9 (CDK20)	unknown	eFIP	12878163

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K53	R53	Biomuta		DOID:1324 / lung cancer [ cosmic ]