iPTMnet Report for Q8IZL8 (PELP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZL8 / PELP1_HUMAN
Protein Name Proline-, glutamic acid- and leucine-rich protein 1
Gene Name Name: PELP1
Synonyms:HMX3,MNAR;
Organism Homo sapiens (Human)

PRO ID PR:Q8IZL8
DAG View
PRO Name proline-, glutamic acid- and leucine-rich protein 1 (human)
Definition A proline-, glutamic acid- and leucine-rich protein 1 that is encoded in the genome of human.
Short Label hPELP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZL8 (PELP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
S7 Phosphorylation PhosphoSitePlus
R32 Methylation PhosphoSitePlus
R34 Methylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
R48 Methylation PhosphoSitePlus
T49 O-Glycosylation GlyGen 23301498, 28510447, 30059200, ...29351928, 34019948, 35083852, 35254053, 33465208
S51 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S245 O-Glycosylation GlyGen 23301498, 28510447, 30059200, ...29351928, 34019948, 35083852, 35254053, 33465208
S251 Phosphorylation PhosphoSitePlus
T348 Phosphorylation IEDB 32387766
K354 Ubiquitination PhosphoSitePlus
T426 O-Glycosylation GlyGen 23301498, 28510447, 30059200, ...29351928, 34019948, 35083852, 35254053, 33465208
S477 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21406692, 23186163, 17081983, ...20807815, 18669648, 20068231
S477 Phosphorylation P11802 (CDK4) PhosphoSitePlus   Signor 20807815
S477 Phosphorylation P24941 (CDK2) PhosphoSitePlus 20807815
S481 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 20068231
S485 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T488 Phosphorylation PhosphoSitePlus   UniProt 21406692
K490 Ubiquitination PhosphoSitePlus
S492 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K495 Ubiquitination PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
T647 Phosphorylation PhosphoSitePlus
S658 Phosphorylation PhosphoSitePlus
T704 O-Glycosylation GlyGen 23301498, 28510447, 30059200, ...29351928, 34019948, 35083852, 35254053, 33465208
T705 O-Glycosylation GlyGen 23301498, 28510447, 30059200, ...29351928, 34019948, 35083852, 35254053, 33465208
S712 O-Glycosylation GlyGen 23301498, 28510447, 30059200, ...29351928, 34019948, 35083852, 35254053, 33465208
S743 Phosphorylation PhosphoSitePlus
T745 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 21406692, ...17081983
T749 Phosphorylation phospho.ELM 17081983
S804 Phosphorylation PhosphoSitePlus
T807 Phosphorylation PhosphoSitePlus
K826 Sumoylation PhosphoSitePlus
Y920 Phosphorylation PhosphoSitePlus   RLIMS-P 17194752
Y920 Phosphorylation P12931 (SRC) PhosphoSitePlus 17194752
S991 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 20807815, 21695158
S991 Phosphorylation P11802 (CDK4) Signor 20807815
S991 Phosphorylation P24941 (CDK2) PhosphoSitePlus   Signor 20807815
T1014 Phosphorylation PhosphoSitePlus
T1022 Phosphorylation PhosphoSitePlus
S1033 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 25788226, 17525332, 23186163, ...21406692, 24786831, 20068231
S1043 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S1073 Phosphorylation PhosphoSitePlus
T1082 Phosphorylation PhosphoSitePlus
T1090 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R48 L48 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]