iPTMnet Report for Q8IZJ1 (UNC5B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZJ1 / UNC5B_HUMAN
Protein Name Netrin receptor UNC5B precursor
Gene Name Name: UNC5B
Synonyms:P53RDL1;ORFNames:UNQ1883/PRO4326;
Organism Homo sapiens (Human)

PRO ID PR:Q8IZJ1
DAG View
PRO Name netrin receptor UNC5B (human)
Definition A netrin receptor UNC5B that is encoded in the genome of human.
Short Label hUNC5B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZJ1 (UNC5B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S41 O-Glycosylation GlyGen 30459171
N222 N-Glycosylation GlyGen 23090970, 24190977
T341 Phosphorylation PhosphoSitePlus
T428 Phosphorylation PhosphoSitePlus   RLIMS-P 32929029
Y452 Phosphorylation PhosphoSitePlus
Y457 Phosphorylation PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
Y511 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
T733 Phosphorylation PhosphoSitePlus
Y737 Phosphorylation PhosphoSitePlus
S800 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus
T804 Phosphorylation PhosphoSitePlus
T807 Phosphorylation PhosphoSitePlus
S869 Phosphorylation PhosphoSitePlus
Y892 Phosphorylation PhosphoSitePlus
Y895 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T733 Phosphorylation HPRD 18452278
Y737 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T341 M341 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T428 M428 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S471 F471 Biomuta DOID:4159 / skin cancer [ cosmic ]
S531 Y531 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S800 I800 Biomuta DOID:2531 / hematologic cancer [ cosmic ]