iPTMnet Report for Q8IZF6 (ADGRG4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZF6 / AGRG4_HUMAN
Protein Name Adhesion G-protein coupled receptor G4 precursor
Gene Name Name: ADGRG4
Synonyms:GPR112;
Organism Homo sapiens (Human)

PRO ID PR:Q8IZF6
DAG View
PRO Name adhesion G-protein coupled receptor G4 (human)
Definition An adhesion G-protein coupled receptor G4 that is encoded in the genome of human.
Short Label hADGRG4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZF6 (ADGRG4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S413 Phosphorylation PhosphoSitePlus
T503 Phosphorylation PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus
T721 Phosphorylation PhosphoSitePlus
T840 Phosphorylation PhosphoSitePlus
K842 Ubiquitination PhosphoSitePlus
T854 Phosphorylation PhosphoSitePlus
S1105 Phosphorylation PhosphoSitePlus
Y1237 Phosphorylation PhosphoSitePlus
T1241 Phosphorylation PhosphoSitePlus
S1250 Phosphorylation PhosphoSitePlus
T1251 Phosphorylation PhosphoSitePlus
S1278 Phosphorylation PhosphoSitePlus
S1382 Phosphorylation PhosphoSitePlus
T1390 Phosphorylation PhosphoSitePlus
S1400 Phosphorylation PhosphoSitePlus
S1408 Phosphorylation PhosphoSitePlus
S1421 Phosphorylation PhosphoSitePlus
S1423 Phosphorylation PhosphoSitePlus
K1541 Ubiquitination PhosphoSitePlus
T1555 Phosphorylation PhosphoSitePlus
S1556 Phosphorylation PhosphoSitePlus
T1694 Phosphorylation PhosphoSitePlus
T1695 Phosphorylation PhosphoSitePlus
S1742 Phosphorylation PhosphoSitePlus
T1965 Phosphorylation PhosphoSitePlus
S1966 Phosphorylation PhosphoSitePlus
T1967 Phosphorylation PhosphoSitePlus
T2114 Phosphorylation PhosphoSitePlus
T2119 Phosphorylation PhosphoSitePlus
S2125 Phosphorylation PhosphoSitePlus
T2130 Phosphorylation PhosphoSitePlus
S2150 Phosphorylation PhosphoSitePlus
S2528 Phosphorylation PhosphoSitePlus
S2620 Phosphorylation PhosphoSitePlus
T2624 Phosphorylation PhosphoSitePlus
T2638 Phosphorylation PhosphoSitePlus
T2785 Phosphorylation PhosphoSitePlus
S2870 Phosphorylation IEDB 35494241
T2930 Phosphorylation PhosphoSitePlus
S3015 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S413 Y413 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S413 C413 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1250 N1250 Biomuta DOID:363 / uterine cancer [ icgc ]
T1251 P1251 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1278 Y1278 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1382 I1382 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1423 A1423 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1742 C1742 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2620 R2620 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T2624 M2624 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T2785 A2785 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S2870 N2870 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3015 R3015 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]