iPTMnet Report for Q8IZF2 (ADGRF5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZF2 / AGRF5_HUMAN
Protein Name Adhesion G protein-coupled receptor F5 precursor
Gene Name Name: ADGRF5
Synonyms:GPR116,KIAA0758;
Organism Homo sapiens (Human)

PRO ID PR:Q8IZF2
DAG View
PRO Name adhesion G protein-coupled receptor F5 (human)
Definition An adhesion G protein-coupled receptor F5 that is encoded in the genome of human.
Short Label hADGRF5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZF2 (ADGRF5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
N179 N-Glycosylation GlyGen 29391424
Y209 Phosphorylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
T236 O-Glycosylation GlyGen 30459171
N256 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424
N301 N-Glycosylation GlyGen 29671580, 29391424
N315 N-Glycosylation GlyGen   UniProt 16335952, 29391424
Y322 Phosphorylation PhosphoSitePlus
N328 N-Glycosylation GlyGen 29391424
N339 N-Glycosylation GlyGen 29391424
N398 N-Glycosylation GlyGen 29391424
T474 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
N505 N-Glycosylation GlyGen 29391424
N540 N-Glycosylation GlyGen 29391424
T604 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
N627 N-Glycosylation GlyGen 23090970, 29391424
N650 N-Glycosylation GlyGen 29391424
S656 Phosphorylation PhosphoSitePlus
S698 Phosphorylation PhosphoSitePlus
N718 N-Glycosylation GlyGen 29391424
N820 N-Glycosylation GlyGen 23090970, 29391424
S939 Phosphorylation PhosphoSitePlus
T941 Phosphorylation PhosphoSitePlus
S1123 Phosphorylation PhosphoSitePlus
S1125 Phosphorylation PhosphoSitePlus
N1160 N-Glycosylation GlyGen 29391424
S1306 Phosphorylation PhosphoSitePlus
S1307 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N301 N-Glycosylation PRO 29671580
T604 Phosphorylation HPRD 18452278
S607 Phosphorylation HPRD 18452278
S608 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 F3 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y322 C322 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T474 K474 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S608 F608 Biomuta DOID:4159 / skin cancer [ cosmic ]
N627 I627 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N650 I650 Biomuta DOID:4159 / skin cancer [ cosmic ]
N650 S650 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S698 N698 Biomuta DOID:1612 / breast cancer [ icgc ]
S698 R698 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S939 L939 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1123 N1123 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1125 F1125 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ]
S1307 Y1307 Biomuta DOID:9256 / colorectal cancer [ cosmic ]