Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZD4 / DCP1B_HUMAN
Protein Name mRNA-decapping enzyme 1B
Gene Name Name: DCP1B
Organism Homo sapiens (Human)

PRO ID PR:Q8IZD4
DAG View
PRO Name mRNA-decapping enzyme 1B (human)
Definition An mRNA-decapping enzyme 1B that is encoded in the genome of human.
Short Label hDCP1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZD4 (DCP1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
K12 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
Y110 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455, 18083107
K128 Ubiquitination PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus   UniProt 23186163
K157 Ubiquitination PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
Y191 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455
K198 Ubiquitination PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y276 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus   UniProt 24275569
K358 Ubiquitination PhosphoSitePlus
T362 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
T373 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
T392 Phosphorylation PhosphoSitePlus   UniProt 23186163
S448 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K455 Ubiquitination PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
T504 Phosphorylation PhosphoSitePlus
S511 O-Glycosylation GlyGen 23301498, 28657654, 29351928
S511 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T518 O-Glycosylation GlyGen 23301498, 28657654, 29351928
S522 O-Glycosylation GlyGen 23301498, 28657654, 29351928
S566 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y110 Phosphorylation HPRD 15592455
Y133 Phosphorylation HPRD 15592455
S147 Phosphorylation HPRD 19651622
Y191 Phosphorylation HPRD 15592455
S275 Phosphorylation HPRD 19413330, 19664994, 16964243, ...18452278
S443 Phosphorylation HPRD 20068231
S511 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y133 H133 Biomuta DOID:363 / uterine cancer [ tcga ]
S147 F147 Biomuta DOID:1909 / melanoma [ tcga ]
T173 K173 Biomuta DOID:3571 / liver cancer [ icgc ]
S186 T186 Biomuta DOID:5041 / esophageal cancer [ icgc ]
Y191 S191 Biomuta DOID:1324 / lung cancer [ tcga ]
T229 R229 Biomuta DOID:3070 / malignant glioma [ tcga ]
S522 F522 Biomuta DOID:1909 / melanoma [ tcga ]