iPTMnet Report for Q8IZ83 (ALDH16A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZ83 / A16A1_HUMAN
Protein Name Aldehyde dehydrogenase family 16 member A1
Gene Name Name: ALDH16A1
Organism Homo sapiens (Human)

PRO ID PR:Q8IZ83
DAG View
PRO Name aldehyde dehydrogenase family 16 member A1 (human)
Definition An aldehyde dehydrogenase family 16 member A1 that is encoded in the genome of human.
Short Label hALDH16A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZ83 (ALDH16A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R5 Methylation PhosphoSitePlus
Y19 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
C350 Methylation IEDB 31844290
K413 Ubiquitination PhosphoSitePlus
R424 Methylation PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
Y482 Phosphorylation PhosphoSitePlus
S488 O-Glycosylation GlyGen 29351928
R535 Methylation PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
R567 Methylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
K618 Acetylation PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
S751 O-Glycosylation GlyGen 30459171
K794 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S124 F124 Biomuta DOID:4159 / skin cancer [ cosmic ]
R424 C424 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S488 L488 Biomuta DOID:4159 / skin cancer [ cosmic ]
R535 C535 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R535 H535 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R567 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
S751 F751 Biomuta DOID:5041 / esophageal cancer [ cosmic ]