Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZ41 / RASEF_HUMAN
Protein Name Ras and EF-hand domain-containing protein
Gene Name Name: RASEF
Synonyms:RAB45;
Organism Homo sapiens (Human)

PRO ID PR:Q8IZ41
DAG View
PRO Name Ras and EF-hand domain-containing protein (human)
Definition A RAS and EF-hand domain-containing protein that is encoded in the genome of human.
Short Label hRASEF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZ41 (RASEF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S74 Phosphorylation PhosphoSitePlus
R76 Methylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
Y399 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
S523 Phosphorylation phospho.ELM   PhosphoSitePlus 16094384
T526 Phosphorylation phospho.ELM   PhosphoSitePlus 16094384
S535 Phosphorylation PhosphoSitePlus
T573 Phosphorylation PhosphoSitePlus
T597 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus
T721 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K366 N366 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S370 F370 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S370 Y370 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
Y399 C399 Biomuta DOID:363 / uterine cancer [ tcga ]
S476 L476 Biomuta DOID:1909 / melanoma [ tcga ]
S535 Y535 Biomuta DOID:1115 / sarcoma [ tcga ]
T573 P573 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S717 C717 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S719 Y719 Biomuta DOID:2531 / hematologic cancer [ tcga ]
T721 P721 Biomuta DOID:4362 / cervical cancer [ tcga ]