iPTMnet Report for Q8IYU2 (HACE1)
Protein Information
| UniProt AC / UniProt ID | Q8IYU2 / HACE1_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase HACE1 |
| Gene Name | Name: HACE1 Synonyms:KIAA1320; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IYU2 |
| PRO Name | E3 ubiquitin-protein ligase HACE1 (human) |
| Definition | An E3 ubiquitin-protein ligase HACE1 that is encoded in the genome of human. |
| Short Label | hHACE1 |
| Category | organism-gene |
DAG ViewQ8IYU2 (HACE1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T20 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S337 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S385 | Phosphorylation | Q13153 (PAK1) | score3 | PhosphoSitePlus Signor | 29362425 | |
| S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S513 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K520 | Acetylation | score1 | PhosphoSitePlus | |||
| Y661 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y677 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y687 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K888 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S385 | T385 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
