iPTMnet Report for Q8IYP9 (ZDHHC23)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYP9 / ZDH23_HUMAN
Protein Name Palmitoyltransferase ZDHHC23
Gene Name Name: ZDHHC23
Organism Homo sapiens (Human)

PRO ID PR:Q8IYP9
DAG View
PRO Name palmitoyltransferase ZDHHC23 (human)
Definition A palmitoyltransferase ZDHHC23 that is encoded in the genome of human.
Short Label hZDHHC23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYP9 (ZDHHC23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S91 Phosphorylation PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
K243 Acetylation PhosphoSitePlus
K247 Acetylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
K255 Acetylation PhosphoSitePlus
K257 Acetylation PhosphoSitePlus
R268 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S200 C200 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K243 N243 Biomuta DOID:363 / uterine cancer [ icgc ]
K247 R247 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
K255 N255 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R268 * Biomuta DOID:3571 / liver cancer [ cosmic ]