iPTMnet Report for Q8IYL3 (C1orf174)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYL3 / CA174_HUMAN
Protein Name UPF0688 protein C1orf174
Gene Name Name: C1orf174
Organism Homo sapiens (Human)

PRO ID PR:Q8IYL3
DAG View
PRO Name UPF0688 protein C1orf174 (human)
Definition A UPF0688 protein C1orf174 that is encoded in the genome of human.
Short Label hC1orf174
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYL3 (C1orf174) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
S22 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
S28 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
S35 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
K63 Acetylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S148 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 20068231
S153 Phosphorylation PhosphoSitePlus
N154 N-Glycosylation GlyGen 29741879
S182 Phosphorylation PhosphoSitePlus
S189 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231, 19690332, 24275569, ...18452278
S217 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S37 C37 Biomuta DOID:3571 / liver cancer [ cosmic ]
T55 M55 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S140 F140 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S153 F153 Biomuta DOID:1319 / brain cancer [ icgc ]
S182 R182 Biomuta DOID:9256 / colorectal cancer [ cosmic ]