iPTMnet Report for Q8IYJ3 (SYTL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYJ3 / SYTL1_HUMAN
Protein Name Synaptotagmin-like protein 1
Gene Name Name: SYTL1
Synonyms:SLP1;ORFNames:SB146;
Organism Homo sapiens (Human)

PRO ID PR:Q8IYJ3
DAG View
PRO Name synaptotagmin-like protein 1 (human)
Definition A synaptotagmin-like protein 1 that is encoded in the genome of human.
Short Label hSYTL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYJ3 (SYTL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus   UniProt 23186163
S231 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S241 Phosphorylation P31749 (AKT1) PhosphoSitePlus   RLIMS-P   Signor 15998322
S301 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus
T562 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S380 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S111 I111 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S159 L159 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S199 L199 Biomuta DOID:1324 / lung cancer [ cosmic ]
S241 L241 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
T562 M562 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ]