iPTMnet Report for Q8IYI8 (ZNF440)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYI8 / ZN440_HUMAN
Protein Name Zinc finger protein 440
Gene Name Name: ZNF440
Organism Homo sapiens (Human)

PRO ID PR:Q8IYI8
DAG View
PRO Name zinc finger protein 440 (human)
Definition A zinc finger protein 440 that is encoded in the genome of human.
Short Label hZNF440
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYI8 (ZNF440) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K48 Ubiquitination PhosphoSitePlus
Y54 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
Y139 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
Y271 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
T391 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K399 Sumoylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
T419 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K427 Sumoylation PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
K461 Acetylation PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S240 C240 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S267 I267 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y271 F271 Biomuta DOID:1324 / lung cancer [ cosmic ]
S335 F335 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S363 N363 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K394 N394 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S513 N513 Biomuta DOID:3571 / liver cancer [ cosmic ]