iPTMnet Report for Q8IYI6 (EXOC8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYI6 / EXOC8_HUMAN
Protein Name Exocyst complex component 8
Gene Name Name: EXOC8
Organism Homo sapiens (Human)

PRO ID PR:Q8IYI6
DAG View
PRO Name exocyst complex component 8 (human)
Definition An exocyst complex component 8 that is encoded in the genome of human.
Short Label hEXOC8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYI6 (EXOC8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S19 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 17924679
K29 Ubiquitination PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
K60 Methylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
T142 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S147 Phosphorylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K329 Sumoylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
S416 Phosphorylation HPRD   PhosphoSitePlus 18452278
K426 Ubiquitination PhosphoSitePlus
Y455 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
T517 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
K699 Ubiquitination PhosphoSitePlus
K702 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 W32 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S147 F147 Biomuta DOID:1319 / brain cancer [ cosmic ]
K370 I370 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S416 L416 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K523 T523 Biomuta DOID:4606 / bile duct cancer [ cosmic ]