iPTMnet Report for Q8IYH5 (ZZZ3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYH5 / ZZZ3_HUMAN
Protein Name ZZ-type zinc finger-containing protein 3
Gene Name Name: ZZZ3
Organism Homo sapiens (Human)

PRO ID PR:Q8IYH5
DAG View
PRO Name ZZ-type zinc finger-containing protein 3 (human)
Definition A ZZ-type zinc finger-containing protein 3 that is encoded in the genome of human.
Short Label hZZZ3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYH5 (ZZZ3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus   UniProt 23186163
S89 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S90 Phosphorylation phospho.ELM 18669648
S113 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S130 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S131 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S135 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K161 Acetylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
T269 O-Glycosylation GlyGen 23301498, 30379171, 35254053
S314 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
S474 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
K605 Ubiquitination PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus   UniProt 23186163
K647 Acetylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
K661 Acetylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
Y670 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus
K701 Acetylation PhosphoSitePlus   UniProt 19608861
K725 Acetylation PhosphoSitePlus
K738 Acetylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S89 Phosphorylation HPRD 18669648, 20068231
S90 Phosphorylation HPRD 18669648
S113 Phosphorylation HPRD 19691289, 20068231, 18452278
S130 Phosphorylation HPRD 19651622, 18669648, 18452278
S131 Phosphorylation HPRD 19651622, 18669648, 18452278
S135 Phosphorylation HPRD 19651622, 18669648, 18452278
S381 Phosphorylation HPRD 20068231
S391 Phosphorylation HPRD 20068231
T393 Phosphorylation HPRD 20068231
S474 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S41 Y41 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S90 F90 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S131 L131 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T269 I269 Biomuta DOID:3571 / liver cancer [ cosmic ]
S381 L381 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S468 F468 Biomuta [ cosmic ]
S606 N606 Biomuta DOID:3571 / liver cancer [ cosmic ]
K701 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]