Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYD8 / FANCM_HUMAN
Protein Name Fanconi anemia group M protein
Gene Name Name: FANCM
Synonyms:KIAA1596;
Organism Homo sapiens (Human)

PRO ID PR:Q8IYD8
DAG View
PRO Name Fanconi anemia group M protein (human)
Definition A Fanconi anemia group M protein that is encoded in the genome of human.
Short Label hFANCM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYD8 (FANCM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T29 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus   UniProt 23186163
K288 Ubiquitination PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
T393 Phosphorylation PhosphoSitePlus
T397 Phosphorylation PhosphoSitePlus
K400 Acetylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
T470 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
Y609 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
Y647 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
K849 Ubiquitination PhosphoSitePlus
K859 Acetylation PhosphoSitePlus
K862 Acetylation PhosphoSitePlus
K867 Acetylation PhosphoSitePlus
K898 Ubiquitination PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
S1045 Phosphorylation PRO   PhosphoSitePlus   RLIMS-P 23698467
S1158 Phosphorylation PhosphoSitePlus
S1162 Phosphorylation PhosphoSitePlus
S1322 Phosphorylation PhosphoSitePlus
T1413 Phosphorylation PhosphoSitePlus
S1417 Phosphorylation PhosphoSitePlus
S1437 Phosphorylation PhosphoSitePlus
S1448 Phosphorylation PhosphoSitePlus
S1571 Phosphorylation PhosphoSitePlus
S1673 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1674 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1686 Phosphorylation PhosphoSitePlus
S1693 Phosphorylation PhosphoSitePlus
S1720 Phosphorylation PhosphoSitePlus
T1721 Phosphorylation PhosphoSitePlus
S1735 Phosphorylation PhosphoSitePlus
T1760 Phosphorylation PhosphoSitePlus
S1783 Phosphorylation PhosphoSitePlus
K1797 Ubiquitination PhosphoSitePlus
S1874 Phosphorylation PhosphoSitePlus
K1916 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T470 Phosphorylation HPRD 18452278
S997 Phosphorylation HPRD 18452278
S1437 Phosphorylation HPRD 19413330


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047369 (hFANCM/Phos:1) pS1045 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S34 C34 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S310 L310 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
K462 * Biomuta DOID:2531 / hematologic cancer [ icgc, tcga ]
K462 N462 Biomuta DOID:3571 / liver cancer [ icgc ]
Y647 C647 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S832 C832 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S1045 F1045 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1448 F1448 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1571 I1571 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1673 * Biomuta DOID:10534 / stomach cancer [ icgc ]
S1874 G1874 Biomuta DOID:1909 / melanoma [ cosmic ]