Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYB8 / SUV3_HUMAN
Protein Name ATP-dependent RNA helicase SUPV3L1, mitochondrial precursor
Gene Name Name: SUPV3L1
Synonyms:SUV3;
Organism Homo sapiens (Human)

PRO ID PR:Q8IYB8
DAG View
PRO Name ATP-dependent RNA helicase SUPV3L1, mitochondrial (human)
Definition An ATP-dependent RNA helicase SUPV3L1, mitochondrial that is encoded in the genome of human.
Short Label hSUPV3L1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYB8 (SUPV3L1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K99 Acetylation PhosphoSitePlus   UniProt 19608861
K201 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K220 Acetylation PhosphoSitePlus   UniProt 19608861
Y379 Phosphorylation PhosphoSitePlus
Y396 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
T403 Phosphorylation PhosphoSitePlus
T604 Phosphorylation PhosphoSitePlus
Y611 Phosphorylation PhosphoSitePlus
T674 Phosphorylation HPRD   PhosphoSitePlus 20068231
K704 Ubiquitination PhosphoSitePlus
K719 Ubiquitination PhosphoSitePlus
S725 Phosphorylation P28482 (MAPK1) HPRD   neXtProt   PhosphoSitePlus   UniProt 18669648, 22028470, 23186163
T744 Phosphorylation PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T604 P604 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T604 A604 Biomuta DOID:363 / uterine cancer [ tcga ]
K749 R749 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]