iPTMnet Report for Q8IYB4 (PEX5L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYB4 / PEX5R_HUMAN
Protein Name PEX5-related protein
Gene Name Name: PEX5L
Synonyms:PEX5R,PXR2;
Organism Homo sapiens (Human)

PRO ID PR:Q8IYB4
DAG View
PRO Name PEX5-related protein (human)
Definition A PEX5-related protein that is encoded in the genome of human.
Short Label hPEX5L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYB4 (PEX5L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T99 Phosphorylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S261 Phosphorylation HPRD 18510355


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T99 P99 Biomuta DOID:363 / uterine cancer [ icgc ]
T106 S106 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S253 I253 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S253 G253 Biomuta DOID:1324 / lung cancer [ cosmic ]
S257 Y257 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K270 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S447 Y447 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]