iPTMnet Report for Q8IYB1 (MB21D2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYB1 / M21D2_HUMAN
Protein Name Nucleotidyltransferase MB21D2
Gene Name Name: MB21D2
Synonyms:C3orf59;
Organism Homo sapiens (Human)

PRO ID PR:Q8IYB1
DAG View
PRO Name nucleotidyltransferase MB21D2 (human)
Definition A nucleotidyltransferase MB21D2 that is encoded in the genome of human.
Short Label hMB21D2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYB1 (MB21D2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S29 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
C144 Methylation IEDB 31844290
S221 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
S305 Phosphorylation HPRD   PhosphoSitePlus 19413330
Y310 Phosphorylation PhosphoSitePlus
C368 Methylation IEDB 31844290
S433 Phosphorylation PhosphoSitePlus
T434 Phosphorylation PhosphoSitePlus
T435 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C144 R144 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S221 F221 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
C368 G368 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S433 R433 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T434 S434 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S436 N436 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S442 Y442 Biomuta DOID:9256 / colorectal cancer [ cosmic ]