iPTMnet Report for Q8IYA6 (CKAP2L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IYA6 / CKP2L_HUMAN
Protein Name Cytoskeleton-associated protein 2-like
Gene Name Name: CKAP2L
Organism Homo sapiens (Human)

PRO ID PR:Q8IYA6
DAG View
PRO Name cytoskeleton-associated protein 2-like (human)
Definition A cytoskeleton-associated protein 2-like that is encoded in the genome of human.
Short Label hCKAP2L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IYA6 (CKAP2L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K18 Ubiquitination PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K30 Methylation PhosphoSitePlus
Y37 Phosphorylation PhosphoSitePlus
K39 Methylation PhosphoSitePlus
T53 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
S114 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K198 Sumoylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
Y204 Phosphorylation UniProt 20388717
S207 O-Glycosylation GlyGen 30379171, 29237092
S213 O-Glycosylation GlyGen 30379171, 29237092
T217 O-Glycosylation GlyGen 30379171, 29237092
K218 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
S234 O-Glycosylation GlyGen 30379171, 29237092
K238 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
Y310 Phosphorylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
Y321 Phosphorylation PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
Y344 Phosphorylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
T382 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus
T449 Phosphorylation PhosphoSitePlus
T451 Phosphorylation PhosphoSitePlus
K456 Acetylation PhosphoSitePlus
K457 Acetylation PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
Y479 Phosphorylation PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
T586 Phosphorylation PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
T621 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
T648 Phosphorylation PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
Y659 Phosphorylation PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus
K682 Ubiquitination PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
T737 Phosphorylation PhosphoSitePlus
T742 Phosphorylation PhosphoSitePlus   UniProt 18669648
S745 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T104 Phosphorylation HPRD 20068231
S392 Phosphorylation HPRD 20068231
S499 Phosphorylation HPRD 16565220
T586 Phosphorylation HPRD 19691289, 16565220
T648 Phosphorylation HPRD 16565220
T685 Phosphorylation HPRD 16565220
T742 Phosphorylation HPRD 18669648, 20068231, 16565220
S745 Phosphorylation HPRD 18669648, 20068231, 16565220


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T53 A53 Biomuta DOID:3571 / liver cancer [ cosmic ]
S105 P105 Biomuta DOID:263 / kidney cancer [ cosmic ]
S114 T114 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S114 C114 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K115 Q115 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S141 P141 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K148 E148 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K185 T185 Biomuta DOID:363 / uterine cancer [ icgc ]
T217 A217 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K243 Q243 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S320 L320 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y344 C344 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S392 I392 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K424 N424 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K457 N457 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S474 Y474 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S499 L499 Biomuta DOID:4159 / skin cancer [ cosmic ]
K556 I556 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y659 F659 Biomuta DOID:1324 / lung cancer [ cosmic ]