iPTMnet Report for Q8IY63 (AMOTL1)
Protein Information
UniProt AC / UniProt ID | Q8IY63 / AMOL1_HUMAN |
Protein Name | Angiomotin-like protein 1 |
Gene Name | Name: AMOTL1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IY63 |
PRO Name | angiomotin-like protein 1 (human) |
Definition | An angiomotin-like protein 1 that is encoded in the genome of human. |
Short Label | hAMOTL1 |
Category | organism-gene |
Q8IY63 (AMOTL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K16 | Ubiquitination | score1 | PhosphoSitePlus | |||
T51 | Phosphorylation | score1 | PhosphoSitePlus | |||
S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
K174 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y191 | Phosphorylation | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
S198 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y218 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y219 | Phosphorylation | score1 | PhosphoSitePlus | |||
T224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
S241 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
S262 | Phosphorylation | score0 | RLIMS-P | 26806348 | ||
S269 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
S295 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
K316 | Methylation | score1 | PhosphoSitePlus | |||
K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
K318 | Methylation | score1 | PhosphoSitePlus | |||
K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
K347 | Ubiquitination | score1 | PhosphoSitePlus | |||
T373 | Phosphorylation | score1 | PhosphoSitePlus | |||
S374 | Phosphorylation | score1 | PhosphoSitePlus | |||
K474 | Ubiquitination | score1 | PhosphoSitePlus | |||
S485 | Phosphorylation | score1 | PhosphoSitePlus | |||
K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
K540 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y546 | Phosphorylation | score1 | PhosphoSitePlus | |||
K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
K594 | Ubiquitination | score1 | PhosphoSitePlus | |||
K611 | Ubiquitination | score1 | PhosphoSitePlus | |||
K625 | Ubiquitination | score1 | PhosphoSitePlus | |||
K649 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y661 | Phosphorylation | score1 | PhosphoSitePlus | |||
K686 | Ubiquitination | score1 | PhosphoSitePlus | |||
K690 | Ubiquitination | score1 | PhosphoSitePlus | |||
T707 | Phosphorylation | score1 | PhosphoSitePlus | |||
T714 | Phosphorylation | score1 | PhosphoSitePlus | |||
T715 | Phosphorylation | score1 | PhosphoSitePlus | |||
S720 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S724 | Phosphorylation | score1 | PhosphoSitePlus | |||
K756 | Ubiquitination | score1 | PhosphoSitePlus | |||
K761 | Ubiquitination | score1 | PhosphoSitePlus | |||
K765 | Ubiquitination | score1 | PhosphoSitePlus | |||
K782 | Ubiquitination | score1 | PhosphoSitePlus | |||
S793 | Phosphorylation | P54646 (PRKAA2) | score4 | PhosphoSitePlus RLIMS-P+ UniProt | 25373897, 23186163 | |
S796 | Phosphorylation | score1 | PhosphoSitePlus | |||
T803 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
S805 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 24275569, 18220336 | ||
S809 | Phosphorylation | score1 | PhosphoSitePlus | |||
S813 | Phosphorylation | score1 | PhosphoSitePlus | |||
S828 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
S876 | Phosphorylation | score1 | PhosphoSitePlus | |||
T877 | Phosphorylation | score1 | PhosphoSitePlus | |||
T879 | Phosphorylation | score1 | PhosphoSitePlus | |||
S892 | Phosphorylation | score1 | PhosphoSitePlus | |||
S895 | Phosphorylation | score1 | PhosphoSitePlus | |||
S900 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T901 | Phosphorylation | score1 | PhosphoSitePlus | |||
T902 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S906 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231, 24275569 | ||
T917 | Phosphorylation | score1 | PhosphoSitePlus | |||
S924 | Phosphorylation | score1 | PhosphoSitePlus | |||
S930 | Phosphorylation | score1 | PhosphoSitePlus | |||
S939 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T51 | Phosphorylation | score0 | HPRD | 17924679 | ||
S52 | Phosphorylation | score0 | HPRD | 17924679 | ||
S61 | Phosphorylation | score0 | HPRD | 17924679 | ||
S241 | Phosphorylation | score0 | HPRD | 20068231 | ||
S295 | Phosphorylation | score0 | HPRD | 18669648, 19691289, 20068231 | ||
S425 | Phosphorylation | score0 | HPRD | 19007248 | ||
S720 | Phosphorylation | score0 | HPRD | 19651622, 19007248, 20068231, ... | ||
S793 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
T801 | Phosphorylation | score0 | HPRD | 20068231 | ||
S805 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
T808 | Phosphorylation | score0 | HPRD | 20068231 | ||
S809 | Phosphorylation | score0 | HPRD | 19007248, 20068231, 19691289 | ||
S900 | Phosphorylation | score0 | HPRD | 20068231 | ||
T901 | Phosphorylation | score0 | HPRD | 20068231 | ||
T902 | Phosphorylation | score0 | HPRD | 20068231 | ||
S906 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
S924 | Phosphorylation | score0 | HPRD | 20068231 | ||
S930 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S198 | L198 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S225 | G225 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S225 | R225 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S262 | I262 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
S295 | Y295 | Biomuta | DOID:2021 / placenta cancer [ cosmic ] | |
S295 | P295 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K316 | N316 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K649 | N649 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K690 | T690 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T715 | M715 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S793 | Y793 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S796 | F796 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S813 | R813 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S828 | N828 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S876 | N876 | Biomuta | [ cosmic ] | |
S876 | I876 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |