iPTMnet Report for Q8IY63 (AMOTL1)
Protein Information
| UniProt AC / UniProt ID | Q8IY63 / AMOL1_HUMAN |
| Protein Name | Angiomotin-like protein 1 |
| Gene Name | Name: AMOTL1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IY63 |
| PRO Name | angiomotin-like protein 1 (human) |
| Definition | An angiomotin-like protein 1 that is encoded in the genome of human. |
| Short Label | hAMOTL1 |
| Category | organism-gene |
Q8IY63 (AMOTL1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K16 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T51 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K174 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y191 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S198 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y218 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T224 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S241 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S262 | Phosphorylation | score0 | RLIMS-P | 26806348 | ||
| S269 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S295 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
| K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K316 | Methylation | score1 | PhosphoSitePlus | |||
| K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K318 | Methylation | score1 | PhosphoSitePlus | |||
| K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K347 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T373 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S374 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K474 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S485 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K540 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y546 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K594 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K611 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K625 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K649 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y661 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K686 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K690 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T707 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T714 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T715 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S720 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| S724 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K756 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K761 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K765 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K782 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S793 | Phosphorylation | P54646 (PRKAA2) | score4 | PhosphoSitePlus RLIMS-P+ UniProt | 25373897, 23186163 | |
| S796 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T803 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
| S805 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 24275569, 18220336 | ||
| S809 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S813 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S828 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| S876 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T877 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T879 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S892 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S895 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S900 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T901 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T902 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S906 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231, 24275569 | ||
| T917 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S924 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S930 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S939 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T51 | Phosphorylation | score0 | HPRD | 17924679 | ||
| S52 | Phosphorylation | score0 | HPRD | 17924679 | ||
| S61 | Phosphorylation | score0 | HPRD | 17924679 | ||
| S241 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S295 | Phosphorylation | score0 | HPRD | 18669648, 19691289, 20068231 | ||
| S425 | Phosphorylation | score0 | HPRD | 19007248 | ||
| S720 | Phosphorylation | score0 | HPRD | 19651622, 19007248, 20068231, ... | ||
| S793 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
| T801 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S805 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
| T808 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S809 | Phosphorylation | score0 | HPRD | 19007248, 20068231, 19691289 | ||
| S900 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T901 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T902 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S906 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
| S924 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S930 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S198 | L198 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| S225 | G225 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S225 | R225 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S262 | I262 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
| S295 | Y295 | Biomuta | DOID:2021 / placenta cancer [ cosmic ] | |
| S295 | P295 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K316 | N316 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K649 | N649 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K690 | T690 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T715 | M715 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S793 | Y793 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S796 | F796 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| S813 | R813 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S828 | N828 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S876 | N876 | Biomuta | [ cosmic ] | |
| S876 | I876 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
DAG View