iPTMnet Report for Q8IY57 (YAF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IY57 / YAF2_HUMAN
Protein Name YY1-associated factor 2
Gene Name Name: YAF2
Organism Homo sapiens (Human)

PRO ID PR:Q8IY57
DAG View
PRO Name YY1-associated factor 2 (human)
Definition A YY1-associated factor 2 that is encoded in the genome of human.
Short Label hYAF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IY57 (YAF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T8 Phosphorylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
K94 Methylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
K99 Methylation PhosphoSitePlus
T134 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S141 O-Glycosylation GlyGen 29351928
S141 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S149 O-Glycosylation GlyGen 29351928
S149 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S153 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S166 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S167 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S173 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 17081983, 20068231
S149 Phosphorylation HPRD 17525332
S166 Phosphorylation HPRD 18669648
S167 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 R6 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S57 F57 Biomuta DOID:4159 / skin cancer [ cosmic ]
T65 I65 Biomuta DOID:363 / uterine cancer [ icgc ]
S174 L174 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S179 C179 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]