iPTMnet Report for Q8IY47 (KBTBD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IY47 / KBTB2_HUMAN
Protein Name Kelch repeat and BTB domain-containing protein 2
Gene Name Name: KBTBD2
Synonyms:BKLHD1,KIAA1489;ORFNames:CGI-73;
Organism Homo sapiens (Human)

PRO ID PR:Q8IY47
DAG View
PRO Name kelch repeat and BTB domain-containing protein 2 (human)
Definition A kelch repeat and BTB domain-containing protein 2 that is encoded in the genome of human.
Short Label hKBTBD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IY47 (KBTBD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K127 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus   UniProt 19690332
K307 Ubiquitination PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
S521 O-Glycosylation GlyGen 30620550


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K127 Q127 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S300 R300 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S521 T521 Biomuta DOID:9256 / colorectal cancer [ cosmic ]