iPTMnet Report for Q8IY37 (DHX37)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IY37 / DHX37_HUMAN
Protein Name Probable ATP-dependent RNA helicase DHX37
Gene Name Name: DHX37
Synonyms:DDX37,KIAA1517;
Organism Homo sapiens (Human)

PRO ID PR:Q8IY37
DAG View
PRO Name probable ATP-dependent RNA helicase DHX37 (human)
Definition A probable ATP-dependent RNA helicase DHX37 that is encoded in the genome of human.
Short Label hDHX37
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IY37 (DHX37) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S91 Phosphorylation HPRD   PhosphoSitePlus 18077418
S106 Phosphorylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
C461 Methylation IEDB 31844290
S510 Phosphorylation PhosphoSitePlus
T613 Phosphorylation PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
K757 Ubiquitination PhosphoSitePlus
K786 Acetylation PhosphoSitePlus
K786 Ubiquitination PhosphoSitePlus
S849 O-Glycosylation GlyGen 30379171
S920 Phosphorylation PhosphoSitePlus
T923 Phosphorylation PhosphoSitePlus
K950 Ubiquitination PhosphoSitePlus
K956 Ubiquitination PhosphoSitePlus
T957 Phosphorylation PhosphoSitePlus
Y1080 Phosphorylation PhosphoSitePlus
K1093 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S106 F106 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S295 N295 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T417 I417 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T613 A613 Biomuta DOID:184 / bone cancer [ cosmic ]
K1093 N1093 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]