iPTMnet Report for Q8IXZ3 (SP8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IXZ3 / SP8_HUMAN
Protein Name Transcription factor Sp8
Gene Name Name: SP8
Organism Homo sapiens (Human)

PRO ID PR:Q8IXZ3
DAG View
PRO Name transcription factor Sp8 (human)
Definition A transcription factor Sp8 that is encoded in the genome of human.
Short Label hSP8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IXZ3 (SP8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
T409 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
T460 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 I11 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S22 I22 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S23 F23 Biomuta DOID:363 / uterine cancer [ icgc ]
S23 C23 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S25 F25 Biomuta DOID:4159 / skin cancer [ cosmic ]
S312 A312 Biomuta DOID:10534 / stomach cancer [ cosmic ]