iPTMnet Report for Q8IXT1 (DDIAS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IXT1 / DDIAS_HUMAN
Protein Name DNA damage-induced apoptosis suppressor protein
Gene Name Name: DDIAS
Synonyms:C11orf82,NOXIN;
Organism Homo sapiens (Human)

PRO ID PR:Q8IXT1
DAG View
PRO Name DNA damage-induced apoptosis suppressor protein (human)
Definition A DNA damage-induced apoptosis suppressor protein that is encoded in the genome of human.
Short Label hDDIAS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IXT1 (DDIAS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
K619 Ubiquitination PhosphoSitePlus
S624 Phosphorylation PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
K733 Ubiquitination PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
K807 Ubiquitination PhosphoSitePlus
K918 Acetylation PhosphoSitePlus
K931 Methylation PhosphoSitePlus
S993 Phosphorylation PhosphoSitePlus
S998 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T47 I47 Biomuta DOID:4159 / skin cancer [ cosmic ]
K500 I500 Biomuta DOID:1324 / lung cancer [ cosmic ]
S521 P521 Biomuta [ cosmic ]
K619 N619 Biomuta DOID:1612 / breast cancer [ cosmic ]
K918 N918 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K931 N931 Biomuta DOID:10534 / stomach cancer [ cosmic ]