iPTMnet Report for Q8IXQ6 (PARP9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IXQ6 / PARP9_HUMAN
Protein Name Protein mono-ADP-ribosyltransferase PARP9
Gene Name Name: PARP9
Synonyms:BAL;
Organism Homo sapiens (Human)

PRO ID PR:Q8IXQ6
DAG View
PRO Name protein mono-ADP-ribosyltransferase PARP9 (human)
Definition A protein mono-ADP-ribosyltransferase PARP9 that is encoded in the genome of human.
Short Label hPARP9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IXQ6 (PARP9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y12 Phosphorylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
C82 Methylation IEDB 31844290
K88 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
Y495 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
K632 Ubiquitination PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
K645 Ubiquitination PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus
K693 Acetylation PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
K743 Ubiquitination PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y12 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K49 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K289 E289 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S362 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S362 L362 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
K459 Q459 Biomuta DOID:1319 / brain cancer [ icgc ]
K488 T488 Biomuta DOID:9256 / colorectal cancer [ cosmic ]