iPTMnet Report for Q8IXQ5 (KLHL7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IXQ5 / KLHL7_HUMAN
Protein Name Kelch-like protein 7
Gene Name Name: KLHL7
Organism Homo sapiens (Human)

PRO ID PR:Q8IXQ5
DAG View
PRO Name kelch-like protein 7 (human)
Definition A kelch-like protein 7 that is encoded in the genome of human.
Short Label hKLHL7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IXQ5 (KLHL7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 O-Glycosylation GlyGen 30379171
R21 Methylation PhosphoSitePlus
R38 Methylation PhosphoSitePlus
C44 Methylation IEDB 31844290
K130 Ubiquitination PhosphoSitePlus
T174 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
C321 Methylation IEDB 31844290
K359 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
T418 Phosphorylation PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
T520 Phosphorylation PhosphoSitePlus
T550 Phosphorylation PhosphoSitePlus
K560 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S239 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K240 N240 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K261 E261 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T418 A418 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K517 R517 Biomuta DOID:10534 / stomach cancer [ cosmic ]