iPTMnet Report for Q8IXK0 (PHC2)
Protein Information
| UniProt AC / UniProt ID | Q8IXK0 / PHC2_HUMAN |
| Protein Name | Polyhomeotic-like protein 2 |
| Gene Name | Name: PHC2 Synonyms:EDR2,PH2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IXK0 |
| PRO Name | polyhomeotic-like protein 2 (human) |
| Definition | A polyhomeotic-like protein 2 that is encoded in the genome of human. |
| Short Label | hPHC2 |
| Category | organism-gene |
DAG ViewQ8IXK0 (PHC2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S275 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S591 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| Y601 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T616 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T617 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T618 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T619 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S621 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
| K632 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K641 | Sumoylation | score1 | PhosphoSitePlus | |||
| K655 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K667 | Acetylation | score1 | PhosphoSitePlus | |||
| K667 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K675 | Acetylation | score1 | PhosphoSitePlus | |||
| S682 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S701 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
| S704 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
| K710 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S733 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| C740 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| S745 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935 | ||
| S751 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K793 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K841 | Sumoylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S591 | Phosphorylation | score0 | HPRD | 18669648, 19691289 | ||
| T619 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S701 | Phosphorylation | score0 | HPRD | 17287340 | ||
| S704 | Phosphorylation | score0 | HPRD | 17287340, 20068231 | ||
| T709 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S733 | Phosphorylation | score0 | HPRD | 17525332 | ||
| S745 | Phosphorylation | score0 | HPRD | 15302935 | ||
| S751 | Phosphorylation | score0 | HPRD | 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S56 | Phosphorylation | score0 | HPRD | 18669648, 19691289 | ||
| T84 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S166 | Phosphorylation | score0 | HPRD | 17287340 | ||
| S169 | Phosphorylation | score0 | HPRD | 17287340, 20068231 | ||
| T174 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S198 | Phosphorylation | score0 | HPRD | 17525332 | ||
| S210 | Phosphorylation | score0 | HPRD | 15302935 | ||
| S216 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S621 | L621 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K710 | N710 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
