iPTMnet Report for Q8IXI2 (RHOT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IXI2 / MIRO1_HUMAN
Protein Name Mitochondrial Rho GTPase 1
Gene Name Name: RHOT1
Synonyms:ARHT1;
Organism Homo sapiens (Human)

PRO ID PR:Q8IXI2
DAG View
PRO Name mitochondrial Rho GTPase 1 (human)
Definition A mitochondrial Rho GTPase 1 that is encoded in the genome of human.
Short Label hRHOT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IXI2 (RHOT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
C79 Methylation IEDB 31844290
K92 Acetylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus   RLIMS-P 35455950, 22078885
S156 Phosphorylation Q9BXM7 (PINK1) PhosphoSitePlus 22078885
Y160 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
T299 Phosphorylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
Y463 Phosphorylation PhosphoSitePlus
Y465 Phosphorylation PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
T558 Phosphorylation PhosphoSitePlus
T561 Phosphorylation PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
K572 Ubiquitination PhosphoSitePlus
T601 Phosphorylation PhosphoSitePlus
Y611 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y276 Phosphorylation HPRD 18452278
T283 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
Y276 Phosphorylation HPRD 18452278
T283 Phosphorylation HPRD 18452278
S589 Phosphorylation PhosphoSitePlus
K645 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y276 Phosphorylation HPRD 18452278
T283 Phosphorylation HPRD 18452278


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049044 (hRHOT1/UbiqLys+) ub PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S156 L156 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K230 N230 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
K330 E330 Biomuta DOID:3571 / liver cancer [ cosmic ]
T558 A558 Biomuta DOID:4606 / bile duct cancer [ cosmic ]