iPTMnet Report for Q8IXI1 (RHOT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IXI1 / MIRO2_HUMAN
Protein Name Mitochondrial Rho GTPase 2
Gene Name Name: RHOT2
Synonyms:ARHT2,C16orf39;
Organism Homo sapiens (Human)

PRO ID PR:Q8IXI1
DAG View
PRO Name mitochondrial Rho GTPase 2 (human)
Definition A mitochondrial Rho GTPase 2 that is encoded in the genome of human.
Short Label hRHOT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IXI1 (RHOT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
T64 Phosphorylation PhosphoSitePlus
C79 Methylation IEDB 31844290
K96 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
C376 Methylation IEDB 31844290
K409 Ubiquitination PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
T517 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
C543 S-Nitrosylation dbSNO 26338901


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S156 L156 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T517 A517 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T517 I517 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]